Martedì 14 luglio 2020
Si terranno i seguenti seminari in videoconferenza meet:

ore 12.00 Prof Cesare Bini, vincitore  procedura valutativa prof. I fascia SSD FIS01 - CODICE CONCORSO 2019POR014 
The upgrade of the ATLAS experiment at LHC for exploring the high-energy frontier of particle physics.

Since more than one decade the Large Hadron Collider at CERN is providing high-intensity pp collisions allowing the 4 main experiments to produce a large amount of physics results. After the first observation of the Higgs boson in 2012, a wide program of precision measurements and searches for signals of new physics has been carried out reducing the uncertainties on the parameters of the Standard Model and at the same time posing strict constraints on the theories beyond the Standard Model.
In order to exploit the potentials of the accelerator and of the experiments, a long-term experimental program based on an upgrade of the accelerator has been defined, aiming to reach the project center of mass energy of 14 TeV and to increase the luminosity up to 5 to 7 times the project value of 1034 cm-2s-1.
This ambitious program is particularly challenging for the experiments, that should go beyond the project performance, so that since several years all experiments have also defined detailed upgrade plans of the detectors.
In this seminar I concentrate on the upgrade of the ATLAS Muon Spectrometer.

After an introduction on the motivations of the upgrade of the Muon Spectrometer, I will describe in some more detail the so called New Small Wheel project that is in this moment one of the main upgrade projects of the experiment, to which I have been involved in these last years together with the ATLAS Rome group.

ore 12.30 Dr. Luca Lamagna, vincitore procedura selettiva RTDB a n. 1 posto presso il Dipartimento di Fisica - SSD FIS/05 
 Tiny needles in the cosmic haystack.

"Precision cosmology" is the common term used today to address the last generation of cosmological observations and studies, which allowed us to achieve percent level sensitivity in the determination of most of the parameters describing our model of the universe.
Such remarkable results were obviously determined by extensive technological R&D, by careful design and planning of observations, and by the wealth of advanced analysis methods developed to deal with the increasing size and complexity of the modern datasets.
But this is just one part of the story: starting from well known case studies in recent cosmological observations, I will provide an argument in support of refining measurement accuracy against the sheer brute force of increasing instrument and data processing performance, and argue how systematics control and instrument modeling must now be regarded as the cornerstones of the cosmologists strategy to face two of the major observational challenges of the next generation: the measurement of primordial B-modes in the polarization of the Cosmic Microwave Background and the hunt for tiny distortions in the spectrum of the CMB.

ore 13.00 Dr. Edoardo Milanetti vincitore procedura selettiva RTDA FIS/07 SC 02/D1 D.D. 248/2019

In silico investigation of protein-protein interactions through shape complementarity characterization

 Interactions among proteins constitute the molecular basis of most processes in living organisms. Therefore, in recent years several research lines have been focused on capturing the determinants of those interactions and on assessing the stability of protein complexes. However, despite the great steps that have been made in the last few years, prediction of the interaction regions between molecules is still an open challenge. In particular, the development of fast and reliable theoretical and computational methods, which may be able to guide and accelerate experiments, is still required today. In this context, the shape of local surface regions in proteins has a key role in predicting protein ability to bind its molecular partners. Here, a new unsupervised computational method is proposed, which efficiently characterizes the shape of any portion of the molecular iso-electron density surface and allows us to evaluate the shape complementarity of protein-protein interfaces employing the 2D Zernike formalism.








L' Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma